In Black and White, a Grandfather and Granddaughter can be found in the Village Gate-Route 12 gate, where the Granddaughter states "My grandpa is going to catch a Pokemon for me! I will become a friend of my Pokemon, and someday we will travel in Unova together!" Her grandfather comments on how difficult it is for him to decide what Pokemon she will meet first.
Fast forward two years later, Hugh makes it his mission to rescue the Purrloin Team Plasma stole from his sister that his late grandfather gave her.
So, is there a confirmed relation between these NPCs?