PokéBase - Pokémon Q&A
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If there are any.

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I'm only in 5th grade, so what does "detrimental" mean?
It means harmful or damaging.

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In Animal Crossing New Leaf: Villagers might move out.
Other than that, nothing really bad would happen.
The Activity log will probably get confused though.

Source: http://www.gamefaqs.com/boards/696959-pokemon-x/67544043 and Experience

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Lol inb4 that has nothing to do with pokemon xD
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Nothing really Pokémon wise... The season would be different in 5th gen, but that isn't harmful.

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In Pokemon ORAS, changing the 3DS time will not help you find more than 1 Mirage Spot in a day. If you do, then get prepared for the punishment of patience. In Pokemon Rumble World, you will not be able to do a second Daily Challenge on the same day and you'll have to wait.

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