In one gen 1 anime episode I couldve swore I saw some fish like in Misty's gym or something because I knew I saw the black stripped fish from nemo in the background....
There actually are real animals, but they were mainly in the early parts of the series.
http://www.youtube.com/watch?v=ep5Xo7nTnR8
http://www.youtube.com/watch?v=c3VTmUgSVsc
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