Below are all the moves that Mewtwo can learn in Generation V, which consists of:
Mewtwo learns the following moves in Generation 5 at the levels specified:
Lv. | Move | Type | Cat. | Power | Acc. |
|---|---|---|---|---|---|
| 1 | Disable | Normal | Status | - | 100 |
| 1 | Confusion | Psychic | Special | 50 | 100 |
| 1 | Barrier | Psychic | Status | - | - |
| 8 | Swift | Normal | Special | 60 | ∞ |
| 15 | Future Sight | Psychic | Special | 100 | 100 |
| 22 | Psych Up | Normal | Status | - | - |
| 29 | Miracle Eye | Psychic | Status | - | - |
| 36 | Mist | Ice | Status | - | - |
| 43 | Psycho Cut | Psychic | Physical | 70 | 100 |
| 50 | Amnesia | Psychic | Status | - | - |
| 57 | Power Swap | Psychic | Status | - | - |
| 57 | Guard Swap | Psychic | Status | - | - |
| 64 | Psychic | Psychic | Special | 90 | 100 |
| 71 | Me First | Normal | Status | - | - |
| 79 | Recover | Normal | Status | - | - |
| 86 | Safeguard | Normal | Status | - | - |
| 93 | Aura Sphere | Fighting | Special | 90 | ∞ |
| 100 | Psystrike | Psychic | Special | 100 | 100 |
Mewtwo does not learn any egg moves.
Mewtwo can be taught these attacks in Generation 5 from move tutors (details):
Move | Type | Cat. | Power | Acc. |
|---|---|---|---|---|
| Fire Punch | Fire | Physical | 75 | 100 |
| Ice Punch | Ice | Physical | 75 | 100 |
| ThunderPunch | Electric | Physical | 75 | 100 |
| Low Kick | Fighting | Physical | - | 100 |
| Snore | Normal | Special | 40 | 100 |
| Icy Wind | Ice | Special | 55 | 95 |
| Sleep Talk | Normal | Status | - | - |
| Iron Tail | Steel | Physical | 100 | 75 |
| Trick | Psychic | Status | - | 100 |
| Role Play | Psychic | Status | - | - |
| Magic Coat | Psychic | Status | - | - |
| Recycle | Normal | Status | - | - |
| Skill Swap | Psychic | Status | - | - |
| Snatch | Dark | Status | - | - |
| Signal Beam | Bug | Special | 75 | 100 |
| Gravity | Psychic | Status | - | - |
| Aqua Tail | Water | Physical | 90 | 90 |
| Drain Punch | Fighting | Physical | 75 | 100 |
| Zen Headbutt | Psychic | Physical | 80 | 90 |
| Wonder Room | Psychic | Status | - | - |
| Magic Room | Psychic | Status | - | - |
| Foul Play | Dark | Physical | 95 | 100 |
Mewtwo can know these moves via events and other sources:
| Move | Type | Cat. | Power | Acc. | Details |
|---|---|---|---|---|---|
| Electro Ball | Electric | Special | - | 100 | Nintendo WFC event |
Mewtwo is compatible with these Generation 5 Technical Machines:
TM | Move | Type | Cat. | Power | Acc. |
|---|---|---|---|---|---|
| 3 | Psyshock | Psychic | Special | 80 | 100 |
| 4 | Calm Mind | Psychic | Status | - | - |
| 6 | Toxic | Poison | Status | - | 90 |
| 7 | Hail | Ice | Status | - | - |
| 8 | Bulk Up | Fighting | Status | - | - |
| 10 | Hidden Power | Normal | Special | - | 100 |
| 11 | Sunny Day | Fire | Status | - | - |
| 12 | Taunt | Dark | Status | - | 100 |
| 13 | Ice Beam | Ice | Special | 95 | 100 |
| 14 | Blizzard | Ice | Special | 120 | 70 |
| 15 | Hyper Beam | Normal | Special | 150 | 90 |
| 16 | Light Screen | Psychic | Status | - | - |
| 17 | Protect | Normal | Status | - | - |
| 18 | Rain Dance | Water | Status | - | - |
| 19 | Telekinesis | Psychic | Status | - | - |
| 20 | Safeguard | Normal | Status | - | - |
| 21 | Frustration | Normal | Physical | - | 100 |
| 22 | SolarBeam | Grass | Special | 120 | 100 |
| 24 | Thunderbolt | Electric | Special | 95 | 100 |
| 25 | Thunder | Electric | Special | 120 | 70 |
| 26 | Earthquake | Ground | Physical | 100 | 100 |
| 27 | Return | Normal | Physical | - | 100 |
| 29 | Psychic | Psychic | Special | 90 | 100 |
| 30 | Shadow Ball | Ghost | Special | 80 | 100 |
| 31 | Brick Break | Fighting | Physical | 75 | 100 |
| 32 | Double Team | Normal | Status | - | - |
| 33 | Reflect | Psychic | Status | - | - |
| 35 | Flamethrower | Fire | Special | 95 | 100 |
| 37 | Sandstorm | Rock | Status | - | - |
| 38 | Fire Blast | Fire | Special | 120 | 85 |
| 39 | Rock Tomb | Rock | Physical | 50 | 80 |
| 40 | Aerial Ace | Flying | Physical | 60 | ∞ |
| 41 | Torment | Dark | Status | - | 100 |
| 42 | Facade | Normal | Physical | 70 | 100 |
| 44 | Rest | Psychic | Status | - | - |
| 47 | Low Sweep | Fighting | Physical | 60 | 100 |
| 48 | Round | Normal | Special | 60 | 100 |
| 52 | Focus Blast | Fighting | Special | 120 | 70 |
| 53 | Energy Ball | Grass | Special | 80 | 100 |
| 56 | Fling | Dark | Physical | - | 100 |
| 57 | Charge Beam | Electric | Special | 50 | 90 |
| 59 | Incinerate | Fire | Special | 30 | 100 |
| 61 | Will-O-Wisp | Fire | Status | - | 75 |
| 63 | Embargo | Dark | Status | - | 100 |
| 68 | Giga Impact | Normal | Physical | 150 | 90 |
| 70 | Flash | Normal | Status | - | 100 |
| 71 | Stone Edge | Rock | Physical | 100 | 80 |
| 73 | Thunder Wave | Electric | Status | - | 100 |
| 77 | Psych Up | Normal | Status | - | - |
| 78 | Bulldoze | Ground | Physical | 60 | 100 |
| 80 | Rock Slide | Rock | Physical | 75 | 90 |
| 84 | Poison Jab | Poison | Physical | 80 | 100 |
| 85 | Dream Eater | Psychic | Special | 100 | 100 |
| 86 | Grass Knot | Grass | Special | - | 100 |
| 87 | Swagger | Normal | Status | - | 90 |
| 90 | Substitute | Normal | Status | - | - |
| 92 | Trick Room | Psychic | Status | - | - |
| 94 | Rock Smash | Fighting | Physical | 40 | 100 |