PokéBase - Pokémon Q&A
5 votes

If you have a good competitive moveset for Mewtwo, post an answer below and upvote the best ones. Movesets for any of its pre-evolutions can also be shared on this thread.

Be sure to include full set details in your post, e.g. items, abilties, natures and EVs. Some detail, including the intended game mode for your set, is also appreciated. Access the full list of guidelines here.

Mewtwo Pokédex and learnset for reference.


edited by
Some of the move sets are different. (Mine!)

FYI, it's the one with the massive images of the Mega forms of Mewtwo.
Mewtwo @ Leftovers
Nature: Modest
EVs: 252 HP 252 Spattack/ 6 Sp Def
Ability: Pressure
Calm Mind
Aura Sphere
Psystrike: STAB, takes care of Fighting and Poison
Calm Mind: A move to just set up
Shadow Ball: To take care of Psychic and Ghost types
Aura Sphere: For Dark type Coverage
Mewtwo with mewtwonite y
Fire Blast
Ice Beam
Mewtwo with calm mind can sweep.
And bulk up/ swords dance

44 Answers

0 votes


Mewtwo is one of the original Ubers of Pokemon, being a gen 1 Pokemon, and being in Ubers since the dawn of Pokemon. Why? Mewtwo, is an extremely versatile Pokemon, and has amazing stats. With the Mega Stones, introduced in Pokemon X and Y, as Mewtwonite X and Y, further reason for it's justification in Ubers. I run Both Mega Mewtwo X AND Y. Mega Mewtwo has one of the best Attack stats in all of Pokemon, and that is what I will be focusing on. Mega Mewtwo X is weak to Ghost, Fairy, and Flying Moves. It isn't weak to Dark, as it is part Fighting. This Mega Pokemon is very versatile, and can be a mixed, special (not advised), or physical sweeper.

This is the move set I am satisfied with, and currently use on my Pokemon X Battle Box Team...


  • Mewtwo @ Mewtwonite X (You Could also use Mega Mewtwo Y as a sweeper too!)

  • Jolly Nature (394 Speed)

  • Perfect 6iv (BTW Hidden Power Dark)

EV Spread: +252 ATK, +252 SPEED, +4 SP DEFENSE.


  • Drain Punch, To regain HP and Counter Dark type Ubers, like Darkrai, which is extremely common in Gen 6 Ubers. Due to Mega Mewtwo X being Psychic - Fighting, Drain Punch gets STAB.

  • Ice Punch, for type coverage, and countering Flying types. Oddly enough, it freezes Pokemon often enough to help me win.

  • Psycho Cut, STAB, and Crit chance. I use this over Zen Headbutt, as it has good Accuracy, buy Zen Headbutt has flinch chance.

  • Poison Jab To counter pesky Geomancy Xerneas with Power Herb, a common pest in Ubers. Poison Jab also has 30% Poisoning chance.

Stone Edge, Zen Headbutt, Aqua Tail, Fire Punch, Thunder Punch, Earthquake, Rock Slide, Bulk Up, Aerial Ace.

Remember that Mewtwo in general is an extremely versatile Pokemon.

I wish that Mewtwo got a physical Dark or Ghost move. Foul Play isn't useful. I wish it got Knock Off, which is actually useful.

Mewtwo is one of the best sweepers ever :)

0 votes

The most annoying mewtwo set ever
Calm mind +1 special attack and special defense
barrier +2 defense
recover sustain
ice beam/toxic you can use either I would use Ice beam so taunt doesn't destroy you
252 hp
252 defense
4 speed
bold nature
This set works best on mewtwo because anything else is weaker or less bulky mewtwos naturally high special attack is why this works along with its great bulk you could use mew but mew is much weaker and slower.

–2 votes

My Mewtwo's moveset in Fire Red:
Works great for Ice and Steel types (Steel resists so many types). Strong move with burning possibility and high PP and I have made it even higher.
For Flying, Ground and Dragon types but also for rival's Tyranitar because it resists all the other moves.
Basically for Psychic and Ghost types but also a good non-Special Attack move for good Special Defenders.
Of course. Mewtwo's Psychic. Try to name more iconic duo. This STAB move exterminates everything so I had to boost its PP to the max just like Flamethrower's.

With these moves you dominate the Pokémon world and easily humiliate elite four (even the 2nd round) by destroying every single Pokémon by one hit (except for Tyranitar which needs two Ice Beams).

With my 100 level Mewtwo with this moves I can easily level up weaker Pokémon with Exp. Share and just walk over the opponents to the Hall of Fame as many times as I want. It doesn't require any healing items.

–4 votes

MEW V.II(Mewtwo)@Leftovers/Mewtwonite X
Ability: Pressure/Steadfast
EVs: 3 Sp. Atk
Impish Nature (+Def, -Sp.Atk)

  • Psystrike: Obivously, Sig, Great Atk and Acc, Inflicts Atk based on Def, not Sp.Def. Coverage vs Fighting and Poison
  • Aura Sphere: Good Atk, Perfect Acc, coverage vs Normal, Ice, Rock, Dark, and Steel
  • Shadow Ball: Good Atk, Great Acc, chance to lower Sp.Def, coverage vs Ghost and Dark
  • Fire Blast: Great Atk, Good Acc, chance to burn, coverage vs Grass, Ice, Bug, and Steel
This set is all wrong:

3 Sp.Atk EV's will not raise it's Sp.Atk even by 1.
Impish is a terrible Nature for Mewtwo.
Why have the Mewtwonite X if you're a Special Attacker?

Were you just trying to troll or something?
This is quite obviously an attempt to troll. Nevertheless, quite a bad one. Try again next time.
This is beautiful I love it
You still have 249 EVs leftover to use. :L
I suggest Timid Nature if going down that Special Sweeper path.