PokéBase - Pokémon Q&A
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Your opponent has Poison Point,Flame Body etc. as their ability.If you attack physically,can Safeguard prevent those negative effects?

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Safeguard prevents the user and its party from being affected by any status condition for five turns except those caused by special abilities, held items or self-inflicted statuses.

So no; you will still be burned/ poisoned/ paralysed/ put to sleep (from effect spore) by your opponent's abilities.

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thanks man!