Question

How many times does the item Focus Sash work?

Answer 1

Focus Sash works only once. It saves you from a potential OHKO. And after that, it's used up and is gone

Source: experience

Comments

Note that this is in-game; if you're battling over wifi, Focus Sash will be used up, but after the battle you will still have the item.

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I know. I put that originally, but I think I made it too confusing. That's why I edited it out earlier.
Perhaps maybe I should write that in again? Because that is true

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Well since marz has it in the comments you dont really have to edit it in :)

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Oh I didn't see the original (obv.) XD Since it's already in comments, I think there's no need to re-edit.