PokéBase - Pokémon Q&A
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No the Pokemon remain the same, but you can't get certain items until you have defeated the Elite 4 such as the fossils in Glittering Cave.

Some areas in the game also cannot be unlocked until you have defeated the Elite 4, notable examples include:

The Friend Safari
Unknown Dungeon
Terminus Cave (Zygarde's Chamber)
Sea Sprit's Den

Hope I helped :)

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I got an Old Amber before beating the Elite four (I remember it 'cause it was my Mega Aerodactyl).
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The answer is no. The pokémon stay the same.

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