Hell yes
Gliscor has and always will be an amazing tank and staller. It's base 125 defense coupled with it's great defensive typing and unique ability allow it to stall and wall like no other. Additionally, it fills a variety of roles, such as physically defensive wall, bulky physical tank, and stealth rock pivot. It's typing and defense allow it to sponge hits from premier OU physical sweepers, including (but not limited to) Mega Medicham lacking an Ice-type move, Terrakion, Landorus-T, Garchomp, Mega Heracross, and Talonflame. If you're going to use Gliscor, use one of the two sets listed below.
Gliscor @ Toxic Orb
Ability: Poison Heal
EVs: 252 HP / 56 Def / 200 Spe
Impish Nature
- Roost
- Fling
- Acrobatics
- Earthquake
If you want to use it as a tank, here's your set. Roost is reliable recovery, Fling poisons an enemy Pokemon and allows you to abuse a 110 BP STAB Acrobatics, and Earthquake provides STAB coverage.
Gliscor @ Toxic Orb
Ability: Poison Heal
EVs: 252 HP / 252 Def / 4 SpD
Impish Nature
- Stealth Rock/Taunt
- Roost
- Toxic
- Earthquake
More of a pivot set, used to set rocks and absorb major physical hits, while retaining the ability to break down opposing walls with the use of Taunt and mainly Toxic. Fairly basic set.