My Sceptile stradegy is using Leaf storm and the White herb with Unburden. But before I go crazy with him, I wanna know if I at least get the speed boost. Does it work with other single use items as well?
As long as you were holding an item and it had been removed, unburden will activate. So if you were to use the white herb, unburden would activate. However the most common strategy that is seen on Sceptile is flying gem+Acrobatics as you do severe damage because acrobatics is boosted by the gem (X1.5) and because you lose the item it's base power will become 110 instead of 55 + you get a speed boost from unburden :)
Yes it will activate Unburden.