My smeargle has lock on and guillotine. If I use lock on then guillotine, will it hit
Source: Experience & Knowledge
Yes it will.
Source: http://bulbapedia.bulbagarden.net/wiki/One-hit_knockout_move
Yes it will,Since Lock on is a move that Makes the accuracy 100% for a turn Then using Guillotine Next, It should hit
Source:Knowledge and playing the game
Hope I helped!