PokéBase - Pokémon Q&A
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I realize this has been already asked, but that was asked back in 2010, before the 225 Pokemon of the last two generations has been added to the games.

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First off, the Pokemon with No Guard-
Machop/Machoke/Machamp
Karrablast
Golett/Golurk
Honedge/Doublade

Unfortunately NONE of these Pokemon have access to the OHKO moves Sheer Cold, Fissure, Guillotine or Horn Drill. Sorry =/

Bulbapedia~

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Looks like I'll have to do 2-turn setups like Mind Reader/Sheer Cold or Smeargle stuff...
in gen 1 u could get a machamp with fissure and it could have no guard but that's the only 1