Yes.
-6 Lvl 1 0- Atk Frillish Poison Sting vs. 252 HP / 252+ Def Kebia Berry Dynamax Leafeon: 1-2 (0.1 - 0.2%) -- possibly the worst move ever
Possible damage amounts: (1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2)
I chose Frillish because it has exceptionally low Attack, and Leafeon because it has rather high Defense. -6 Level 1 Frillish with an Attack-reducing Nature against max EV and Defense-boosting Nature Dynamax Leafeon with a Kebia Berry (which reduces damage from Poison moves) is pretty much a guarantee that your Frillish isn't going to be doing a thing.