Question

What are all the differences between Black 2 and White 2?

Comments

Besides version exclusives, Black 2's plot involves Zekrom and black Kyurem, and White 2's plot involves Reshiram and white Kyurem. Black City and challenge mode are exclusive to Black 2, and White Forest and easy mode are exclusive to White 2. You can unlock all of these on both versions of the game by using the Unova Link. The battle HUD and HUD panel that displays the location name are black in Black 2 and white in White 2. Route 4, Mistralton City, Opelucid City, Reverse Mountain, and Victory Road look different in the different versions. They also have different opening cutscenes.
[source][1]


  [1]: https://bulbapedia.bulbagarden.net/wiki/Pok%C3%A9mon_Black_and_White_Versions_2

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Some items, like the Grip Claw, Wide Lens, and Light Clay, are only non-repeatably obtainable in one version. Several Funfest Missions are only playable in one version. The Iron Key and Iceberg Key are exclusives without using Unova Link to transfer them. Pinsir, Heracross, Hariyama, and Medicham in Hidden Grottoes have different encounter rates depending on version.