Meta Battle Subway PokeBase - Pokemon Q&A
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I hah'd when I saw the title.

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Pokerus is a disease you can catch by batteling another Pokemon
Basically if you make contact with that Pokemon you will catch pokerus which doubles evs
the chance of finding a Pokemon with pokerus is a 1/3 of a chance catching a shiny according to bulbapedia
If you have pokerus in your team it will spread after a while

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It's completely random and is slightly more common then shiny pokemon and seem to appear only once in each game.

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