As long as they are not already poisoned, yes
It is possible to burn, freeze, paralyze, poison or put to sleep anything holding a Flame or Status Orb, as long as it is not already statused. However, with gliscor this is difficult, as it is immune to Thunder Wave and tends to carry protect, preventing the opponent from statusing it while Toxic Orb activates. As such, one;s only hope is to hit it with a status-inducing move when it switches in, and most players will avoid the risk of status and not switch in like that. So yes, it is possible, but very hard to do, especially against experienced players.