There are only a couple difference in the games with the Pokemon you can get (and color palette)
For Red the version exclusives are Ekans/Arbok Odish/Gloom/Vileplume Mankey/Primeape Growlithe/Arcanine Scyther and Electabuzz
For Red the Game Corner difference are Abra costs 180, Clefairy costs 500, Dratini costs 2800, Scyther costs 5500, and Porygon costs 9999
For Blue the version exclusives are Sandshrew/Sandslash Vulpix/Ninetales Meowth/Persian Bellsprout/Weepinbell/Victreebel Magmar and Pinsir
For Blue the Game Corner differences are Abra costs 120, Clefairy costs 750, Drantini costs 4600, Pinsir costs 2500, and Porygon costs 6500
Source: https://gamerant.com/pokemon-red-blue-similarities-differences/