Apparently all the answers have vanished
As of the start of the anime, Brock was 15. He may be 16-17, but since no one ages in the anime, it is hard to tell.
Misty and May are both 10-12 (again, we can't tell we can't tell the passing of time in the anime).
In the anime, Brock acts towards Ash, Misty, May, Dawn, etc. as a caretaker or older brother. He is also more interested in Nurse Joy, Officer Jenny or any other characters he falls in love with, and doesn't show any sign of being in love with May or Misty.
Also, the anime is a show for kids, and Brock's behaviour is most likely just for humour. I doubt they would make him fall in love with any of Ash's travelling companions, as it might be taken as inappropriate.
So, to conclude, I would think no.