PokéBase - Pokémon Q&A
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I'm not sure how in my 300+ hours of playing Pokemon I have never found a shiny but somehow I got Pokerus which has a 1/20,000ish chance infection. The Pokemon that has the virus is in my Heartgold version, and I'm starting a new playthrough on my Black version. Heartgold is a Gen. 4 game and Black is a Gen. 5. I'm not even sure if Black has Pokerus but I want to know if the virus could even be transferred between generations. It would speed up my playthrough and help me tremendously. Does anyone know anything about this?

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https://pokemondb.net/pokebase/194241/pokemon-pokerus-transferred-poketransfer-poketransporter
This question doesn't ask something quite as broad, but I think they are similar enough to be considered duplicates.
I edited the question so make the difference between this and the other question more pronounced.

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PokeRus is transferable across Gens if the transferred Pokemon is infected with the virus, unfortunately not if the virus is cured.

PokeRus is available in all games starting Generation 2 :)

Source: This and experience

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Thank you.