Let's see here...
Drifblim's Ghost-Flying typing gives it access to the neat STAB Shadow Ball. Outside of that...not good. It doesn't even get Flare Boost yet, it gets that in Gen 5. Without it, it's outclassed by Haunter and Staraptor. Drifblim has a large movepool but the moves it gets are unremarkable; its best options for coverage are Thunderbolt and Psychic, which don't really fit on its movepool well. It's also not very strong and is not as bulky as it seems. Haunter is faster and more versatile, and has a lot of good options it can use. Same applies to Staraptor.
And if you thought Drifblim was mediocre, Lopunny is just straight up bad. Playthroughs are focused on doing damage, and that's something Lopunny isn't good at, with its base 76 Attack. It being a friendship evolution also means it's hard to get and it really isn't worth your time at all.
TL;DR you're better off going with something like Garchomp, since both of these Pokemon are unspectacular and share a type with the superior Staraptor. Also you should be using Lucario over Toxicroak.